hrp0089p1-p139 | Fetal, Neonatal Endocrinology and Metabolism P1 | ESPE2018

Transient Neonatal Iatrogenic Hypothyroidism due to Iodinated Contrast

Harenstam Ulrika , Hafstrom Ola , Reims Annika

Introduction: Iodine is necessary for thyroid hormone synthesis, but when exposed to large quantities, iodine may have an inhibitory effect on hormone synthesis leading to hypothyroidism, known as the Wolff-Chaikoff effect. Newborns may be exposed to iodine through various events in early life. In 2012 three index cases with suspected iatrogenic hypothyroidism due to iodinated contrast exposure were discovered at the Neonatal department, The Queen Silvia Children’s Hospit...